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FEATURED TECH
Methods for Establishing Drug Supersaturation from a Porous Host
Technology #2019-069
Applications
- Solubilization of candidate drug compounds that are otherwise poorly soluble in water
- Enables oral delivery of active pharmaceutical ingredients
- Increases drug solubilization beyond normal equilibrium (i.e., leads to supersaturation)
- MOF scaffold comprised of safe, non-toxic compounds
- Current MOF scaffold shown to be generalizable
- Approach may be extended to other, related MOFs
- Suitable for clinical application